When and how much to take
NSAIDs should ideally be taken with some food, or at least with milk or yoghurt to avoid irritation of the gastric mucosa (. the inner lining of the stomach). It is important not to exceed the recommended dose to avoid possible serious side-effects. There is also no benefit in taking more than a certain dose, since these drugs have a ceiling effect. This means that above a certain dose, taking even more of this medication will not yield any extra beneficial effects, but will considerably increase the risk for side-effects.
The fact is that anabolic steroids do present various health risks – they are not without their faults and potential risks, as with anything. However, the context under which they are utilized presents a vast difference in how much of a risk is being taken. Responsible and judicious anabolic steroid use among healthy adult males is a significantly different situation in comparison to anabolic steroid use among children, teenagers, and females. Within the context of healthy adult male anabolic steroid use, the associated and proposed risks plummet by a massive degree, and from what we already know from studies referenced above, the average anabolic steroid user is in fact not teenagers and nor are they athletes, but are healthy adult males in the median age range of 25 – 35 years of age. Other more recent studies have also supported this fact among steroids statistics, where a 2006 study that surveyed 500 anabolic steroid users found that almost 80% of these users were not competitive athletes or bodybuilders but instead average adult physically active males  . Furthermore, the majority of anabolic steroid users are short-term users that do not engage in lifetime use (either in cycles or constant use), and that the rate of actual lifetime use among anabolic steroid users was found to be % for males, and % for females5. What this means is that only % and % of all male and female anabolic steroid users respectively will engage in lifetime use (mostly via subsequent cycles), while the rest will only utilize anabolic steroids once or a handful of times during their life.
NSAIDs increase the risk of potentially fatal, stomach and intestinal adverse reactions (for example, bleeding, ulcers, and perforation of the stomach or intestines ). These events can occur at any time during treatment and without warning symptoms. Elderly patients are at greater risk for these adverse events. NSAIDs (except low dose aspirin) may increase the risk of potentially fatal heart attacks, stroke , and related conditions. This risk may increase with duration of use and in patients who have underlying risk factors for heart and blood vessel disease. Therefore, NSAIDs should not be used for the treatment of pain resulting from coronary artery bypass graft ( CABG ) surgery.